Making new drugs and bringing them to market is a lengthy process than can take over a decade to complete,…
Cancer
Cancer imaging: Main scan types
An imaging examination (also known as scan) is the term used for non-invasive (i.e. no surgical intervention) visualization of structures…
Types of cancer immunotherapy
The immune system is the body’s defence mechanism for clearing infections, pathogens and tumors. When our immune system is healthy…
What determines the success of cancer immunotherapy ?
Cancer immunotherapy, a revolutionary treatment that aims to boost the patient’s immune system to enable it to effectively seek and…
Improving outcome of cancer immunotherapy through drug combinations
Cancer immunotherapy is a new type of treatment aimed at bolstering the immune system to enable it to more effectively…
CAR-T immune cell therapy: comparing systemic and local delivery
Cell-based immune therapy is a type of immunotherapy that works by direct transfer of activated cancer-fighting immune cells to the…
How do immune checkpoint inhibitors work?
Immune checkpoint inhibitors are drugs that block the inhibitory (negative) signals founds on immune cells and which act as a…
Why does CAR-T immune cell therapy not work well in solid tumors?
T cell therapy of cancer is a form of immunotherapy that works by infusing the patient with T cells (either…
Oncology: the difference between umbrella and basket clinical trials
Drug development is a lengthy and costly process with an average of 10+ years for a (successful) drug to make…
Medical imaging: What is the difference between PET and SPECT?
PET (positron emission tomography) and SPECT (single photon emission computed tomography) are two of the main imaging methods used in…
How does tumor metabolism influence immunotherapy?
Immunotherapy using drugs such as anti-PD-1/PD-L1 checkpoint inhibitors, is an anti-cancer strategy that can achieve durable clinical benefit in many…
Metabolism: Tumours eat their way into survival and beyond
Metabolism refers to the biochemical reactions that allow food and other molecules to be processed (either made or broken down)…